GC00006

Accession No

GC00006

Strain Name

SD.Abcb1b(tm)-GC/ILAS

Status

Freezed embryo

Gene/full name

Abcb1b /

ATP-binding cassette, subfamily B (MDR/TAP), member 1B

Gene ID

24646

Background

Sprague Dawley

Type

Knockout

Donor

Lianfeng Zhang, Yuanwu Ma,Jing Ma, Xu Zhang, Wei Chen

Disease & Phenotype

drug metabolism，drugresistance， toxicity 

Construction Description

Genotyping Protocols

MDR1-rat-check-F：GCTACAATGACATGTCCTACCCAAT  

MDR1-rat-check-R：AGTCTTGATTCTGCCAGCCTAGTC   

Mating System

Heterozygote x Heterozygote;

Reference

1.马婧,陈炜,张旭.多药耐药基因1(Abcb1)敲除和人源化大鼠模型的建立,《中国比较医学杂志》,2015.